星形细胞瘤完整版.pptx

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Lecturer:GuoXiangClassificationandDiagnosisofastrocytoma(星形细胞瘤)

MorbidityofAstrocytomaAstrocytictumor78%GliomaPrimarybraintumor40%5orbidity

TypeofAstrocytomaWHOclassificationⅠ~ⅣⅠ级毛细胞型星形细胞瘤、室管膜下巨细胞星形细胞瘤Ⅱ级弥漫型星形细胞瘤Ⅲ级间变型星形细胞瘤Ⅳ级胶质母细胞瘤PilocyticastrocytomaANDSubependymalgiantcellastrocytomasDiffuseastrocytomaAnaplasticastrocytomaGlioblastoma

Subependymalgiantcellastrocytomas-GradeⅠReddish-yellowpimpleschromosomaldisorder染色体疾病epiloia(结节性硬化)8Y~18Y(male-to-femaleratio=3:1)subependymalnodulescontrast-enhancehydrocephalus脑积水favorableclinicaloutcome红黄色丘疹

T1T2T1-enhanceCTnon-contrastM16y

Pilocyticastrocytoma-GradeⅠChildrenCerebellumhemispheresorvermisSolidandcysticpartNormaltissuesolidnodulecysticmassCSFindensityonNCCTMRI:ahigh-signal-intensitycystsurroundingaiso-intensitymuralnoduleonT2ContrastenhancementwithbothCTandMRIvermis

F62YT1T2T1-enhance

Pathology

弥漫型星形细胞瘤属于交界性肿瘤,容易复发,且恶性度有不断增加的趋势,最终发展为胶质母细胞瘤。Grade-ⅡDiffuseastrocytomaGrade-ⅢAnaplasticastrocytomaGrade-ⅣGlioblastomaDiffuseastrocytoma-GradeⅡborderlinetumorsurgerymalignancywillbehigherrecurCharacteristic

ImagingCharacteristicBrainstemorsupratentorialwhitematterpoorlydefinedborderLow-densityonCTslightlyCSFNosignificantenhancement

NoorslightlyenhancementCysticchangeT1WIhypointensitysignalT2WIhyperintensitysignalF54Y

SurgicalfieldandSpecimenThetumorshoweddiffuselyinfiltratedgrowing.NOhemorrhageandnecrosis.

Anaplasticastrocytoma-GradeⅢthetumorenhanceddistinctly

T1-enhanceFLAIRT1T2T1Glioblastoma-Grade-ⅣAdulthoodMixeddensityorsignallesionHemorrhageandnecrosisContrast-enhance

Becausethetreatmentofastrocytomaismainlybasedonpathologicaltype,soitwillbeveryhelpfultomakeanaccuratediagnosistothelevelofcells.

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