内科-肝疾病及门脉高压.pptxVIP

1of67第三十八章肝疾病第一节解剖生理概要(Anatomyandphysiology)GeneralDescriptionandTopography

2of67第三十八章肝疾病第一节解剖生理概要(Anatomyandphysiology)FunctionalAnatomy

3of67第三十八章肝疾病第一节解剖生理概要(Anatomyandphysiology)FunctionalAnatomyandSurgery

4of67第三十八章肝疾病第一节解剖生理概要(Anatomyandphysiology)FunctionalAnatomyandImaging

5of67第三十八章肝疾病第一节解剖生理概要(Anatomyandphysiology)HepaticMicrocirculation

MicrovilliHepatocytesinplatesBilecanaliculusSPACEOFDISSEFenestratedEndothelialcellsSINUSOIDKupffercellSTELLATECELLHEPATOCYTEENDOTHELIALCELLKUPFFERCELLSTELLLATECELL

7of67第三十八章肝疾病第一节解剖生理概要(Anatomyandphysiology)BloodFlow1500mL/minute25%ofthecardiacoutputHepaticA.:Blood25~30%,Oxygen46~60%Portalv.:Blood70~75%

8of67第三十八章肝疾病第一节解剖生理概要(Anatomyandphysiology)FunctionEnergyFunctionalheterogeneityBileformationEnterohepaticcirculationBilirubinmetabolismCarbohydratemetabolismLipidmetabolismProteinmetabolismVitaminmetabolismCoagulationMetabolismofdrugsandtoxinRegeneration

9of67第三十八章肝疾病第一节解剖生理概要(Anatomyandphysiology)AssessmentofLiverFunctionVariable1Point2Points3PointsBilirubinlevel2mg/dL2–3mg/dL3mg/dLAlbuminlevel3.5g/dL2.8–3.5g/dL2.8g/dLInternationalnormalizedratio1.71.7–2.22.2EncephalopathyNoneControlledUncontrolledAscitesNoneControlledUncontrolledChild-Pughclass:ClassA=5–6points;ClassB=7–9points;ClassC=10–15pointsChild-PughScore

10of67第三十八章肝疾病第二节偶发肝脏肿块的诊断与鉴别诊断（Occasionallivermass）

11of67第三十八章肝疾病第三节