布地奈德联合沙丁胺醇雾化吸入治疗AECOPD疗效及对肺功能影响.docx

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布地奈德联合沙丁胺醇雾化吸入治疗AECOPD疗效及对肺功能影响

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【摘要】目的：探究布地奈德联合沙丁胺醇雾化吸入治疗AECOPD疗效及对肺功能影响。方法：按照入院顺序随机抽取我院自2015年2月至2017年2月收治的82例AECOPD患者，分为观察组（n=41）和对照组（n=41）。对照组进行布地奈德治疗，观察组在对照组的基础上联合沙丁胺醇治疗。比较两组的治疗效果、肺功能、临床症状消失时间、不良反应发生率以及生活质量。结果：与对照组的治疗效果比较，观察组的较高；与对照组的肺功能比较，观察组的较优；与对照组的哮鸣音、湿罗音、咳嗽以及喘憋等症状消失时间比较，观察组的较短；与对照组的生活质量比较，观察组的较高，差异显著（P0.05）；与对照组的不良反应发生率比较，观察组的无明显差异（P0.05）。结论：布地奈德联合沙丁胺醇雾化吸入治疗AECOPD，有效改善了患者的临床症状以及肺功能，降低了不良反应发生率，提升了患者的生活质量，安全可靠，值得借鉴和推广。

【关键词】布地奈德；沙丁胺醇；雾化吸入；AECOPD

EffectofbudesonidecombinedwithsalbutamolinhalationonAECOPDandpulmonaryfunction

XuHongli

(Thepeopleshospitalofxinjincountyisbreathingmedicine,Chengdu,sichuanprovince,611430)

[abstract]objective:toexploretheeffectofbudesonidecombinedwithalbuterolatomizationinhalationfortreatmentofAECOPDanditseffectsonlungfunction.Methods:82casesofAECOPDpatientsadmittedbyourhospitalfromFebruary2015toFebruary2017wererandomlyselectedaccordingtotheorderofadmission,pidedintoobservationgroup(n=41)andcontrolgroup(n=41).Thecontrolgroupwastreatedwithbudesonideandtheobservationgroupwastreatedwithalbuterolbasedonthecontrolgroup.Thetwogroupswerecomparedwiththetreatmenteffect,pulmonaryfunction,clinicalsymptomdisappearancetime,adversereactionrateandqualityoflife.Results:comparedwiththecontrolgroup,theobservationgroupwashigher.Comparedwiththelungfunctionofthecontrolgroup,theobservationgroupwasbetter.Comparedwiththecontrolgroupofasthma,wet,cough,andasthma,theobservationgroupwasshorter.Comparedwiththecontrolgroup,theobservationgroupwashigherandthedifferencewassignificant(P0.05).Comparedwiththeadversereactionsofthecontrolgroup,therewasnosignificantdifferenceintheobservationgroup(PBBB00.05).Conclusion:budesonidecombinedsalbutamolaerosolinhalationinthetreatmentofAECOPD,effectivelyimprovethepatientsclinicalsymptomsandlungfunction,reducetheincidenceofadversereactions,andimprovethepatientsqualityoflife,safeandreliable,isworthreferenceandpromotion.

[keywords]Albuterol;Atomizationinhalation;AECOPD

COPD（慢性阻塞性肺疾病）是临床上较为常见的