TSQ Endura_Quantiva Quick Reference Guide from Joshua Kline(串联质谱仪器).docx

TSQ Endura_Quantiva Quick Reference Guide from Joshua Kline(串联质谱仪器).docx

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PAGE8

TSQ

TSQQuantivaandTSQEnduraQuickReferenceGuide

ThisguidecontainsanoverviewofOperationsfortheTSQQuantivaandTSQEnduraoperatingsystemsandXcalibursoftwarewithtopicsorganizedbyworkflow.ForfurtherinformationpleaserefertotheXcaliburUserGuides,instrumentspecificTSQmanualsandtheHelpprovidedwithinXcalibur.ThemanualsareprovidedasPDFsontheXcaliburinstallationCD.

Contents:

?TSQSourceMaintenance

?TSQCalibrationGuidelines

?CompoundOptimizationforSRMAnalysis

?StartingXcalibur

?InstrumentSetup–SRMMethodEditor

?SequenceSetup

?QualBrowser

?QualitativeProcessingSetup

?QuantitativeProcessingSetup

?QuanBrowser

XReport

TSQSourceMaintenance

TSQSourceMaintenance

ChangingtheIonTransferCapillary:

Theiontransfercapillarycanberemovedwiththeremovaltoolwhilstthesystemstillundervacuum.Cleanthecapillarybysonicationin1%aqueousformicacid,followedbyrinsinginwaterandfinallysonicationinmethanol.

Beforeremovingtheiontransfercapillarypleaseloweritstemperaturebelow150oC.

Fordiagramsreferto“TSQQuantivaandTSQEnduraHardwareManual”locatedintheThermoInstrumentsmanualsfolder.

APIStackMaintenance

TocleantheAPIregionthesystemmustbevented.FirstturnofftheElectronicsServiceSwitchtoprotectthesystemagainstanypowersurge.Turnoffthevacuumbyswitchingoffthemainpowerswitch(white).Waitfor10minutesandremovetheAPIstack.

InspecttheEDIForS-lensandexitlensundermagnificationforanylint,particulates,andsamplebuilduporcoatings.

SonicatetheEDIForS-lensfor10–15min.ina50:50methanol/watersolutionora1%solutionofLiquinoxinwater.Ifasonicatorisnotavailable,dothefollowing:

CleantheEDIForS-lenswithaChemtronics?chamoistipswabwitha1%solutionofLiquinox?inwater.

Usea6000gritMICRO-MESH?polishingswabtoclean

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