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Endocr Pract. 2013 Mar-Apr;19(2):327-36. AACE comprehensive diabetes management algorithm 2013. Garber AJ, Abrahamson MJ, Barzilay JI, Blonde L, Bloomgarden ZT, Bush MA, Dagogo-Jack S, Davidson MB, Einhorn D, Garvey WT, Grunberger G, Handelsman Y, Hirsch IB, Jellinger PS, McGill JB, Mechanick JI, Rosenblit PD, Umpierrez G, Davidson MH. PMID:[PubMed - in process] The Individualized Target HbA1c: A New Method for Improving Macrovascular Risk and Glycemia Without Hypoglycemia and Weight Gain 二甲双胍的处方不断上升,磺脲类不断下降,胰岛素控制使用,TDZ初期得到临床认可,但2006-2007证实其心血管风险后出现明显回落 evaluation of guideline recommendations on oral medications for type 2 diabetes mellitus Cardiovascular disease and intensive glucose control in type 2 diabetes mellitus: moving practice toward evidence-based strategies Vasc Health Risk Manag. 2009;5:859-71. Epub 2009 Nov 2. Cardiovascular disease and intensive glucose control in type 2 diabetes mellitus: moving practice toward evidence-based strategies. Meier M, Hummel M. Source Clinic for Hypertension and Nephrology, Hannover, Germany. kfnh_hannover@web.de Initiating oral glucose lowering therapy with metformin in type 2 diabetic patients_an evidence based strategy to reduce the burden of late developing diabetes complications 2010年中国指南的重要更新:2型糖尿病药物治疗的首选药物应是二甲双胍;如果没有二甲双胍的禁忌症,该药物应该一直保留在糖尿病的治疗方案中 * STATEmENT by AN american association of clinical endocrinologists american college of endocrinology consensus panel on type 2 diabetes mellitus_an algorithm for glycemic control Managing Type 2 Diabetes: Going Beyond Glycemic Control J Manag Care Pharm. 2008 Jun;14(5 Suppl B):s2-19. Managing type 2 diabetes: going beyond glycemic control. Stolar MW, Hoogwerf BJ, Gorshow SM, Boyle PJ, Wales DO. Source Northwestern University Medical School, Chicago, IL 60611, USA. markstolar@ 只要没有禁忌,二甲双胍是初始治疗的首选药物 Meier M, et al. Vasc Health Risk Manag. 2009;5:859-71. 基于新兴数据,ADA/EASD的指南放宽了应用二甲双胍的条件 二甲双胍可用于心室功能异常不严重的糖尿病患者 二甲双胍可用于GFR低至30mL/min的糖尿病患者 Inzucchi SE, et al. Diabetes
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