戊型肝炎病毒的危害性及流行状况分析.docVIP

. . 戊型肝炎病毒的危害性及流行状况分析 戊型肝炎病毒（Hepatitis E virus, HEV，下简称戊肝病毒）为正链RNA病毒，是戊型肝炎病毒科（Hepeviridae）戊型肝炎病毒属（hepevirus）的唯一成员，目前被认为是亚洲、中东和非洲国家急性肝炎的最重要病因之一 ADDIN EN.CITE EndNoteCiteAuthorPurcell/AuthorYear2008/YearRecNum89/RecNumrecordrec-number89/rec-numberref-type name=Journal Article17/ref-typecontributorsauthorsauthorPurcell, R. H./authorauthorEmerson, S. U./author/authors/contributorsauth-addressLaboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8009, USA. rpurcell@/auth-addresstitlestitleHepatitis E: an emerging awareness of an old disease/titlesecondary-titleJ Hepatol/secondary-title/titlesperiodicalfull-titleJ Hepatol/full-title/periodicalpages494-503/pagesvolume48/volumenumber3/numberkeywordskeywordDeveloped Countries/keywordkeywordDeveloping Countries/keywordkeywordHepatitis A virus/genetics/pathogenicity/keywordkeywordHepatitis E/*diagnosis/*etiology/prevention amp; control/keywordkeywordHepatitis E virus/genetics/pathogenicity/keywordkeywordHumans/keywordkeywordViral Hepatitis Vaccines/therapeutic use/keyword/keywordsdatesyear2008/yearpub-datesdateMar/date/pub-dates/datesaccession-nuaccession-numurlsrelated-urlsurl/entrez/query.fcgi?cmd=Retrieveamp;db=PubMedamp;dopt=Citationamp;list_uids/url/related-urls/urls/record/Cite/EndNote[1]。 戊肝病毒主要分为4个基因型，1型主要分布于亚洲、非洲、南美的发展中国家，2型主要分布于墨西哥、乍得、尼日利亚等国；3型存在于发达国家的本土戊肝病人和世界各地的猪体内；4型主要来自日本、中国、台湾的发达地区和印度，也存在于猪体内 ADDIN EN.CITE EndNoteCiteAuthorDalton/AuthorYear2008/YearRecNum88/RecNumrecordrec-number88/rec-numberref-type name=Journal Article17/ref-typecontributorsauthorsauthorDalton, H. R./authorauthorBendall, R./authorauthorIjaz, S./authorauthorBanks, M./author/authors/contributorsauth-addressPeninsula College of Medicine and Dentistry, Royal Cornwall Hospital Trust, Truro, UK. harry.dalton@rcht.cornwall.nhs.uk/auth-addresstitlestitleHepatitis E: an emerging infection in developed countries/titlesecondary-titleLancet Infect Dis/secondary-title/titlespe