附加放射粒子植入局部期肺外科治疗.ppt

附加放射性粒子植入局部期肺癌外科治疗 广州呼吸病研究所 广州医学院第一附属医院 胸外科 广州市 510120 摘要 目的 探讨在选择性局部晚期期肺癌扩大手术治疗中附加应用I-125 放射性粒子胸内植入的其临床疗效及并发症. 方法 近几年我们 对30 例局部晚期肺癌在进行减状性或姑息性手术, 同时附加胸内植入I-125放射性粒子, 植入I-125粒子数为10--40粒, 均采用适形铺盖植入方式, 术 后7--14天内同步进行化疗与其它疗法治疗.. 结果 无手术死亡,术后均采用胸片,CT观察, 粒子分布满意, 疼痛, 胸水症状和体征均有较大缓解, 全组未发生放射性肺炎, 也无其它相关的并发症, 结沦 在局部晚期肺癌的减量性或估息性手术中, 附加进行放射性粒 子I--125植入,可进一步提高疗效, 而且并发症轻 关键词 局部晚期肺癌; 手术; 放射粒子; 植入 Intraoprative radioactivity I-125 seed Permanent imptlant for Local Advanced Non Small Lung Cancer Abstract Objective:To study the clinical efficacy and toxicity of using radioactivity I-125 seed Permanent imptlant in surgenry for Local Advanced Non Small Lung Cance Methods : from Oct.2003 to Oct. 2006,The I-125 seeds were implanted into 30 patients with Local Advanced Non Small Lung Cancer in surgenry .TheNumber of seeds was 10—40,The chemotherype were performed in 10 to 14days after opration Results : No oprative death, The distribution of seeds and complications were review by CT and X-ray after treatment.The distribution of seeds was satisfactiory in all patients.There had not one case whose radiation pneumonia had not occurred. Conclusion: It is a mild complication,safety and effective method that I-125 seed permanent implants in surgenry for Local Advanced Non Small Lung Cance. Key words: Local Advanced Non Small Lung Cancer; radioactivity I-125 seed, implantation 目前两大严峻问题: 肺癌发病率越来越高 肺癌一经确诊大部分己属晚期 一个新的口号 对于晚期肺癌---------- 老年肺癌 ---------- 多学科,多手段 局部广泛侵犯的肺癌--- 参与的综合治疗 己有远处转移的肺癌--- 临床常遇到的问题: 肺癌患者瘤块巨大-------- 有严重阻塞性肺---------- 非手术 ?