nhd在高原地区胸外科凝血功能异常患者治疗中的应用及疗效分析word论文.docxVIP

AbstractBackground:Cruorincludesvascularendothelialcelldamaged,cruorreaction, anti-freezingandfibrinolysismechanism,whichleadtocruorformationtogether.In theplateauenvironment,anoxiamotivateintrinsicandextrinsiccoagulationpathway, bloodcoagulationfactorattrittoreduce,whichmakesthepatientsexpressing bleedingtendency,includesAPTT,PTextension;levelofFIB,PLTdecline;vascular bedincrease;vesselwallbrittlenessandbloodvolumerise.whenprocess thoracotomy,thepatientswillmanifest ashighamountofbleeding,itcausehigh degreeofdependencyofplasma.Inthoracicsurgerytherapy,physicianuse normovolaemichaemodilution(NHD)therapytoimprovethepatientscoagulation function andPostoperative Hemorrhage.Objective:Thesubjectofthisstudyisby meansoftestratingandmacroscopicrating of NHD teamanditspostoperation.Discuss the therapic effectof NHD aboutplateau regionThoracicsurgerypatientswhoaccompanybloodcoagulationdisorders preliminary.Methods:ContrastiveanalysisdifferenceofNHDgroupwithcontrolgroupabout APTT,PT,FIB,HB,HCT,PLTandSpO2;contrastiveanalysisdifferenceofNHDgroup andcontrolgroupAPTT,PT,FIB,HB,HCT,PLT,amountofbleeding,timeof drainagetube,requirementofplasmawhenthemexperiencethoracotomy.Control group is untreated patients previously.Results: NHDgroupAPTT,PTis obviously shorterthan control group（p0.01）,FIBandSpO2haveahigherlevelthancontrolgroup(p0.05),PLThavenosignificant difference than control group(p0.05);after receive thoracotomy, NHD groupAPTT,PTis obviously shorter than control group（p0.01）,FIB、HB、HCT、PLThavenosignificantdifference(p0.05)thancontrolgroup,NHDgroupchestfluid,timeof drainage tube, volume of plasma is obviously much lessthancontrol group（p0.01）Conclusion：1.Plateau region Thoracic surgery patients who accompany bloodcoagulationdisordersreceiveNHDtherapygettingcoagulationfunction improvement,APTT,PT is shorten; level of FIB is increased; blood viscosity isdecreased,whichmanifestHB,HCTdeceased;levelofSpO2isincreased.2.Patients whoreceiveNHDtheirbloodcoagulationimprovementafter