恶性肿瘤化学治疗与静脉血栓栓塞性疾病的关系研究进展-肿瘤药学.pdf

- 162 - 肿瘤药学 2011 年 6 月第 1 卷第 3 期 Anti-tumor Pharmacy, June 2011, Vol.1, No.3 ·综述· 恶性肿瘤、化学治疗与静脉血栓栓塞性疾病 的关系研究进展★ 1 1* 2 罗明尧 ，舒畅 ，周晓 1 （中南大学湘雅二 医院血管外科 ，湖南长沙， 4 100 11； 2 湖南省肿瘤 医院头颈外科 ，湖南长沙，4 100 13） 摘要 ：静脉血栓栓塞性疾病是恶性肿瘤的常见并发症之一，尤其是对于接受化学治疗的患者，其发 生率更高。静脉血栓栓塞性疾病可引发致命性后果，从而增加恶性肿瘤患者的死亡率。本文拟对恶性肿 瘤、化学治疗与静脉血栓栓塞性疾病的关系作一总结，并对其临床表现、治疗、预后进行综述，以期提高 认识，做好防治工作。 关键词 ：恶性肿瘤；化疗；静脉血栓栓塞性疾病 中图分类号 :R730　文献标识码 :A　文章编号：2095-1264(2011)03-0162-04 The Progress of Research on Relationship of Malignancy, Chemotherapy and Venous Thromboembolism Disease 1 1* 2 Luo Mingyao , Shu Chang , Zhou Xiao 1 ( Dep artment of vascular surgery, the second Xiangya Hosp ital of Central South Uni- 2 versity, Changsha, Hunan, 410011; Dep artment of Head and Neck Surgery, Hunan p rovincial Tumor Hosp ital, Changsha, Hunan, 4010013) Abstract: Venous thromboembolism disease (VTED) is one of the most common complications of malignancies. Moreover, a higher incidence of VTED has been recorded in cancer patients who had chemotherapy. As VTED can result in lethal outcome, such as fatal pulmonary embolism, the mortality will increase obviously in those patients with malignant tumors and VTED simultaneously. For the purpose of preve