IWRP 公共英语 沈阳药科大学.ppt

Research Paper Student Id: 201330361 Name: Meng Guangpeng Major: Organic Chemistry Well known magazines of organic chemistry Tetrahedron IF:2.817 Organic Letters IF:4.802 J Amer Chem Soc（Journal of the American Chemical Society） IF:6.51 Organometallics IF:2.875 Chemical Reviews IF:21.036 The Typical Paper The Biology and Chemistry of Antifungal Agents: A Review Muthu K Kathiravan, Amol B Salake, Aparna S Chothe, Prashik B Dudhe, Rahul P Watode, Maheshwar S Mukta, Sandeep Gadhwe Title This review addresses the areas such as the underlying mechanisms, eight different targets such as ergosterol synthesis, chitin synthesis, ergosterol disruptors, glucan synthesis, squalene epoxidase, nucleic acid synthesis, protein synthesis, microtubules synthesis. The clinically employed drugs along with the current research work going on worldwide on different heterocycles are discussed. In recent advances various heterocycles including imidazole, benzimidazole etc., twenty three scaffolds and their lead identification are discussed Introduction Fungal infections pose a continuous and serious threat to human health and life. These fungal infections in humans can be classified into allergic reactions to fungal proteins, toxic reactions to toxins present in certain fungi and infections. Healthy individuals are susceptible to a host of superficial, cutaneous, subcutaneous and in certain instances, systemic infections that cause a variety of conditions ranging from Athletes foot and nail infections to severelife-threatening disseminated disease. Many fungal infections are caused by opportunistic pathogens that may be endogenous or acquired from the environment. Frame Introduction Reference Results Discussion Methods Data Analysis of the review Analysis of the review Analysis of the review Summary Through the investigation, I know a lot of relevant professional journals, which is great helpful to my future study and experiments. * * topic The name of