XELOX方案化疗联合微波消融治疗胃癌术后肝转移疗效分析.pdfVIP

I研究原著— Q!笙 县 XELOX方案化疗联合微波消融治疗胃癌术后肝转移 疗效分析 李红梅 ，代晓强 (咸阳市 中心医院，陕西 咸阳，712000) 摘要 ：日的探讨XELOX方案化疗联合微波消融对胃癌根治术后肝转移灶的疗效。方法将 58例胃癌根治术后肝转移的 患者随机分成观察组 (3O例)及对照组(28例)，观察组采用XELOX方案化疗联合超声引导下微波消融，对照组采用单 纯XELOX方案化疗，统计两组近期有效率、毒副反应发生率、1年和2年生存率。结果 观察组近期有效率高于对照组 (P0．05)；观察组毒副反应总发生率与对照组比较 ，差异无统计学意义(PO．05)；观察组的 1年、2年生存率均高于对 照组(．P0．05)。结论 采用XELOX方案化疗联合微波消融对 胃癌根治术后位置表 浅和体积较小的肝转移灶疗效好，可延 长患者生存期。 关键词：胃癌；肝脏转移；微波消融；卡培他滨 中图分类号：R735 文献标志码：A 文章编号：2096—1413(2017)01—0006—03 TheeffectanalysisofXELOX program chemotherapycombinedwithmicrowave ablationonhepaticmetastasesfrom gastriccancer LIHong—mei，DAIXiao—qiang (XianyangCenteralHospital，Xianyang712000，China) ABSTRACT：ObjectiveToinvestigatetheeffectofXELOXprorgam chemotherapycombinedwithmicrowaveablation onhepaticmetastasesfrom gastriccancer．Mem0dsFifry—eightpatientswithhepaticmetastasesfrom gastriccancerafter radicalgastrectomywererandomlydivided into twogroups．Theobservationrgoup with 30 patientswastreated with XELOX prorgam chemotherapycombinedwithultrasound-guidedmicrowaveba lation．Thecontrolrgoupwith28patients wastreatedwithXELOX program chemotherapy．Theshort-term effectiverate，the incidenceoftoxicityaswellasone ortwoyearsurvivalratewererecordedand comp~ed．ResultsTh eshort-temr effectiverateofobservation groupwas obviouslyhigherthanthatofthecontrolgroup (P0．05)；theincidenceoftoxicityhadnostatisticaldifferencebewteen thetwogroups 0．05)；the1，2-yearsurvivalratesoftheobservationrgoupwerehigherthanthoseofthecontrolgroup (P0．05)．Conclusion Forthepatientswithhepaticmetastasesrfom gastriccancerafterradicalgastrectomywith superficiallocationandsmal