牛蒡的药理作用研究进展.PDF

·综 述· 牛蒡的药理作用研究进展 曹旭1 2 1* ，曹剑锋 ，陈靠山 (1.皖南医学院，安徽 芜湖 241000 ；2. 山东大学生命科学学院，济南 250100) 摘要：目的 介绍牛蒡的药理作用研究进展，为进一步利用牛蒡提供依据。方法 通过查阅近20 年的国内外文献，对牛 蒡的药理作用进行概述。结果 牛蒡具有抗肿瘤、抗炎及免疫调节、抗菌、抗病毒、抗糖尿病、抗氧化、肝保护作用、 抗疲劳、降血脂、治疗勃起功能障碍及其他多种药理作用，其中对牛蒡的免疫调节、抗癌作用及其治疗糖尿病的作用研 究较多，具有潜在的开发应用价值。笔者所在实验室关于牛蒡治疗勃起功能障碍作用的研究为牛蒡开发利用提供了新的 方向。结论 牛蒡具有较大的开发利用价值，特别是在治疗慢性疾病方面。 关键词：牛蒡；药理作用；研究进展 中图分类号：R285.5 文献标志码：A 文章编号：1007-7693(2012)11-0975-05 Advances in Pharmacological Effects of Arctium Lappa L . 1 2 1* CAO Xu , CAO Jianfeng , CHEN Kaoshan (1.Wannan Medical College, Wuhu 241000, China; 2.School of Life Sciences, Shandong University, Jinan 250100, China) ABSTRACT: OBJECTIVE To introduce advances in the pharmacological effects of Arctium lappa L., and to provide scientific basis for the further utilization. METHODS Consulted domestic and foreign literatures in recent 20 years and provided an overview of the pharmacological effects of burdock. RESULTS The advances in pharmacological effects such as antitumor, anti-inflammatory, immune modulation, antimicrobial, antiviral, antidiabetic, antioxidant, hepatoprotective effect, anti-fatigue, lipid-lowering and treatment erectile dysfunction of Arctium lappa L. were given. It was universally studied that Arctium lappa L. possess effects of immune regulation, anti-cancer and treatment diabetes with the potential development value. The research on the efficacy of burdock to treat erectile dysfunction in our laboratory provided a new direction for burdock development and utilization. CONCLUSION It’s found that the pharmacological effects of burdock have great development value, especially in the treatment of chronic diseases. KEY WORDS: Arctium lappa L.; pharmacological effects; research advances 牛蒡(Arctium lappa L.)又名东洋