替勃龙片联合双唑泰泡腾片治疗老年性阴道炎疗效观察.PDF

·852 · 现代药物与临床 Drugs Clinic 第 32 卷 第 5 期 2017 年 5 月 替勃龙片联合双唑泰泡腾片治疗老年性阴道炎疗效观察 付 敏 信阳市第四人民医院 妇产科，河南 信阳 464100 摘 要：目的 探讨替勃龙片联合双唑泰泡腾片治疗老年性阴道炎的临床疗效。方法 选取 2016 年 1 月—2016 年 7 月在信 阳市第四人民医院接受诊治的老年性阴道炎患者 90 例，所有患者根据用药方案的不同分为对照组和治疗组，每组各 45 例。 对照组每晚清洁外阴后于阴道深处置入双唑泰泡腾片，1 片/次，1 次/d 。治疗组在对照组基础上口服替勃龙片，1 片/次， 1 次/d 。两组患者均连续治疗3 个月。观察两组的临床疗效，比较两组的临床症状消失时间和生活质量。结果 治疗后，对 照组和治疗组的总有效率分别为 77.78%、95.56%，两组比较差异有统计学意义（P ＜0.05 ）。治疗后，治疗组外阴瘙痒、阴 道黏膜充血和阴道分泌物消失时间明显短于对照组，两组比较差异具有统计学意义（P ＜0.05 ）。治疗后，两组躯体功能、心 理功能、社会功能和物质生活评分均明显升高，同组治疗前后比较差异有统计学意义（P ＜0.05 ）；且治疗组这些观察指标的 升高程度明显优于对照组，两组比较差异具有统计学意义（P ＜0.05 ）。结论 替勃龙片联合双唑泰泡腾片治疗老年性阴道炎 具有较好的临床疗效，可缩短临床症状消失时间，改善生活质量，具有一定的临床推广应用价值。 关键词：替勃龙片；双唑泰泡腾片；老年性阴道炎；临床症状消失时间；生活质量 中图分类号：R984 文献标志码：A 文章编号：1674 - 5515(2017)05 - 0852 - 04 DOI:10.7501/j.issn.1674-5515.2017.05.023 Clinical observation of Tibolone Tablets combined with Metronidazole Clotrimazole and Chlorhexidine Acetate Effervescent Tablets in treatment of senile vaginitis FU Min Department of Obstetrics and Gynecology, Xinyang Fourth People’s Hospital, Xinyang 464100, China Abstract: Objective To investigate the clinical effect of Tibolone Tablets combined with Metronidazole Clotrimazole and Chlorhexidine Acetate Effervescent Tablets in treatment of senile vaginitis. Methods Patients (90 cases) with senile vaginitis in Xinyang Fourth People’s Hospital from January 2016 to July 2016 were enrolled in this study. According to the difference treatment plan, patients were randomly divided into control and treatment groups, and each group had 45 cases. Patients in the control group were placed with Metronidazole Clotrimazole and Chlorhexidine Acetate Effervescent Tablets into vagina deep at bedtime after cleaning the vulva, 1 tablet/time, once daily. Patients in the treatment group were po administered wi