Transoral Robotic Surgery for Oropharyngeal Carcinoma and .ppt

* At one and two year time points for at risk patients, overall survival was 55/58 (94.8%) and 33/41 (80.5%), respectively. At one and two year time points for at risk patients, disease specific survival was 55/56 (98%) and 33/36 (91.7%) * At one and two year time points for at risk patients, overall survival was 55/58 (94.8%) and 33/41 (80.5%), respectively. At one and two year time points for at risk patients, disease specific survival was 55/56 (98%) and 33/36 (91.7%) * At one and two year time points for at risk patients, overall survival was 55/58 (94.8%) and 33/41 (80.5%), respectively. At one and two year time points for at risk patients, disease specific survival was 55/56 (98%) and 33/36 (91.7%) * * 12 surgery alone, 13 surgery plus radiation, 31 (one patient had radiation prior for lymphoma, 1 patient had liver mets diagnosed shortly after treatment) 3 patients recommended adjuvant therapy, but refused * Overall survival as a function of HPV status (1/blue line, HPV-, 2/green line, HPV+) 31 patients assessed; 22 HPV+ and 9 patients HPV- * * AngKK JCO23(13)2005 : 50 OP, 30% ShileySG-OtoHNS2006, 143,3,455-9: 48% G tube required * * * * * Overall survival with respect to HPV status P=0.87 (log rank) Comparison of outcomes related to HPV status 30: Fakhry et al. J. Natl Cancer Inst. 2008 100:261-269. 31: Worden et al. J Clin Oncol; 26:3138-3146 2008 Swallowing function There is a wide range of cited percentage of people after chemoradiation requiring gastrostomy tube. This is cited from 3% to approximately 50%.5,34,35 Ang et al cited the long term need for gastrostomy tubes in 30% of those with OPSCC treated with chemoradiation.34 Shiley et al cited the need for gastrostomy tube in 48% of those with OPSCC treated with chemoradiation.35 In our cohort 91% (50/55) of at risk patients had the gastrostomy tube removed. Conclusions TORS appears to be oncologically sound, with adequate margins of resection as well as satisfactory preliminary overall and dis